Jessicas Lindvall
Curriculum vitae
I am currently persuing my first post-doc in the Bioinformatics group headed by principal investigator Associate Professor Torbjørn Rognes
at the Department of Informatics facilitated at the University of Oslo, Norway.
My main project is microarray analysis with regards to cellular stress responses that results in DNA damage and triggers DNA repair. Together with Gard Thomassen
and Karin Lagesen (both PhD students in Ass. Prof. Torbjørn Rognes group) I have been a part of designing novel high-density tiling arrays covering the genomes of E.coli and N.meningitidis, respectively, with regards of different cellular stress responses and these projects are in their finishing stage.
Also, I am in close collaboration with several high profiled researchers in the field of DNA repair in Oslo. Dr. Hilde Nilsen is a successful young researcher in the field of C. elegans and DNA damage response. Also, projects are driven in the species of S. pombe where tiling arrays have been used to search for intergenic transcripts after DNA damage. Here, I am working with Prof. Erik Boye and his PhD student, Cathrine Arnason Bøe.
By education, I am a chemical engineer from the Mälardalen University but I went on earning my PhD in Molecular Cell Biology from the Karolinska Institutet in Stockholm, Sweden.
As a PhD student I was a member of the Unit for Molecular Cell Biology and Gene Therapy Sicience
working on signal transduction and gene expression analysis in B-lymphocytes. My thesis, which I defended the fall 2005, was entitled
Molecular dissection of B-lymphocyte signalling using gene expression profiling.
Scientific work
Articles (* indicate invited Review articles, $ indicate Corresponding author)
2002
Islam TC et al, Expression profiling in transformed human B cells:
influence of Btk mutations and comparison to B cell lymphomas using filter and oligonucleotide arrays, Eur J Immunol. 2002 Apr;32(4):982-93
Lindvall JM et al, Interaction of Btk and Akt in B cell signaling, Biochem Biophys Res Commun. 2002 May 24;293(5):
1319-26
2003
Islam TC et al, High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13
and differential expression of Cyclin D1 in mantle cell lymphoma, Leukemia. 2003 Sep;17(9):1880-90
*$ Lindvall JM et al, In silico tools for signal
transduction research, Brief Bioinform. 2003 Dec;4(4):315-24
2004
$ Lindvall JM et al, Gene expression profile of B cells from Xid mice and Btk knockout mice, Eur J Immunol. 2004 Jul;34(7):1981-91
2005
*$ Lindvall JM et al, Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling, Immunol Rev. 2005 Feb;203:200-15
$ Lindvall JM et al, Differential expression and molecular characterisation of Lmo7,
Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells, Cell Immunol. 2005 May;235(1):46-55
2006
$ Lindvall JM et al, Distinct gene expression signature in Btk-defective T1 B-cells.
, Biochem Biophys Res Commun. 2006 Jul 28;346(2):461-9
2007
*$ Blomberg KEM, Smith CIE and Lindvall JM, Gene expression signatures in primary immunodeficiencies: the experience from human disease and mouse models., Curr Mol Med. 2007 Sep;7(6):555-66
2008
Hasan M et al, Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice., Immunology. 2008 Feb;123(2):239-49. Epub 2007 Aug 28
Ranheim T et al, Genome-wide expression analysis of cells expressing gain of function mutant D374Y-PCSK9., J Cell Physiol. 2008 Nov;217(2):459-67
Nawaz HM et al, Expression profiling of chicken DT40 lymphoma cells indicates clonal selection of knockout and gene reconstituted cells., Biochem Biophys Res Commun. 2008 Dec 12;377(2):584-8. Epub 2008 Oct 16
Peer-reviewed conference articles
Driscoll R et al [all authors contributed equally], Nucleotide Excision Repair, Meeting: DNA Repair: from Molecular Mechanism to Human Disease, Noordwijkerhout, The Netherlands, April 2-7, 2006
Book chapters
Lindvall JM et al, Gene expression in lymphomas and immunodeficiencies provides new insights into B-lymphocyte development. "New Research Communications on Messenger RNA", Nova -Editorial 2006
Contact address
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Jessica Lindvall, PhD
Institutt for informatikk (IFI)
Senter for Bioinformatikk
Visiting address:
Gaustadalleen 25
NO-0373 Oslo
Postal address:
Postboks 1080 Blindern
NO-0316 Oslo
Norway
tel: +4722844785
fax: +4722844782
e-mail: jessli@ifi.uio.no
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