Group Members



  1. J. Schmidtke, B. Pape, U. Krengel, U. Langenbeck, D.N. Cooper, E. Breyel & H. Mayer (1984)
    Restriction fragment length polymorphisms at the human parathyroid hormone gene locus,
    Hum. Genet. 67, 428-431. [PubMed]

  2. E.F. Pai, W. Kabsch, U. Krengel, K.C. Holmes, J. John & A. Wittinghofer (1989)
    Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the tri-phosphate conformation,
    Nature 341, 209-214. [PubMed]

  3. E.F. Pai, U. Krengel, G.A. Petsko, R.S. Goody, W. Kabsch & A. Wittinghofer (1990)
    Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 Ĺ resolution: implications for the mechanism of GTP hydrolysis,
    EMBO Journal 9, 2351-2359. [PubMed]

  4. U. Krengel, I. Schlichting, A. Scherer, R. Schumann, M. Frech, J. John, W. Kabsch, E.F. Pai & A. Wittinghofer (1990)
    Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules,
    Cell 62, 539-548. [PubMed]

  5. U. Krengel, I. Schlichting, A. Scheidig, M. Frech, J. John, A. Lautwein, F. Wittinghofer, W. Kabsch & E.F. Pai (1991)
    The three-dimensional structure of p21 in the catalytically active conformation and analysis of oncogenic mutants, The Superfamily of ras-related genes, ed. by D.A. Spandidos, Plenum Press New York,
    NATO Series A: Life Sciences 220, 183-193.

  6. F. Wittinghofer, U. Krengel, J. John, W. Kabsch & E.F. Pai (1991)
    Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant,
    Environmental Health Perspectives 93, 11-15. [PubMed]

  7. S.M. Franken, A.J. Scheidig, U. Krengel, H. Rensland, A. Lautwein, M. Geyer, K. Scheffzek, R.S. Goody, H.R. Kalbitzer, E.F. Pai & A. Wittinghofer (1993)
    Three-dimensional structures and properties of a transforming and a nontransforming Gly-12 mutant of p21H-ras,
    Biochemistry 32, 8411-8420. [PubMed]

  8. K.-H. Schröter, U. Krengel, A. Scherer & E.F. Pai (1994)
    Refined structure of ras-p21 at 1.1 Ĺ resolution,
    Zeitschrift für Kristallographie, Supplement 8, 473.

  9. U. Krengel, H.J. Rozeboom, K.H. Kalk & B.W. Dijkstra (1996)
    Crystallization and preliminary crystallographic analysis of endo-1,4-ß-xylanase I from Aspergillus niger,
    Acta Cryst. D52, 571-576. [PubMed]

  10. U. Krengel & B.W. Dijkstra (1996)
    Three-dimensional structure of endo-1,4-ß-xylanase I from Aspergillus niger: Molecular basis for its low pH-optimum,
    J. Mol. Biol. 263, 90-97. [PubMed]

  11. U. Krengel, R. Lapatto, K.H. Kalk & B.W. Dijkstra (1996)
    Refined X-ray structure of Antistasin at 1.9 Ĺ resolution,
    Hasylab Jahresbericht, 331-332.

  12. R. Lapatto, U. Krengel, H.A. Schreuder, A. Arkema, B. de Boer, K.H. Kalk, W.G.J. Hol, P.D.J. Grootenhuis, J.W.M. Mulders, R. Dijkema, H. Theunissen & B.W. Dijkstra (1997)
    X-ray structure of antistasin at 1.9 Ĺ resolution and its modelled complex with blood coagulation factor Xa,
    EMBO J. 16, 5151-5161. [PubMed]

  13. U. Krengel, K.-H. Schröter, H. Hoier, A. Arkema, K.H. Kalk, P. Zimniak & B.W. Dijkstra (1998)
    Crystal structure of a murine alpha-class glutathione S-transferase involved in cellular defense against oxidative stress,
    FEBS Lett. 422, 285-290. [PubMed]

  14. U. Krengel & Y. Xue (1998)
    Crystallographic analysis of 4 mutants of chorismate mutase from B. subtilis,
    Max-LAB Activity Report, 220-221.

  15. M. Ökvist, J.-E. Bryntesson, L. Sjölin & U. Krengel (1999)
    Crystal structure of creatine kinase from rabbit muscle,
    Max-LAB Activity Report, 283.

  16. K. Mahr, G.P. v. Wezel, C. Svensson, U. Krengel, M.J. Bibb & F. Titgemeyer (2000)
    Glucose kinase of Streptomyces coelicolor A3(2): large-scale purification and biochemical analysis,
    Antonie van Leeuwenhoek 78, 253-261. [PubMed]

  17. P. Kast, C. Grisostomi, I.A. Chen, S. Li, U. Krengel, Y. Xue & D. Hilvert (2000)
    A strategically positioned cation is crucial for efficient catalysis by chorismate mutase,
    J. Biol. Chem. 275 (47), 36832-36838. [PubMed]

  18. M. Ökvist, N. Bonander, A. Sandberg, G.B. Karlsson, U. Krengel, Y. Xue & L. Sjölin (2002)
    Crystal structure of the double azurin mutant Cys3Ser/Ser100Pro from Pseudomonas aeruginosa at 1.8 Å resolution; its folding-unfolding energy and unfolding kinetics,
    Biochim. Biophys. Acta 1596, 336-345. [PubMed]

  19. C. Svensson, S. Teneberg, C.L. Nilsson, A. Kjellberg, F.P. Schwarz, N. Sharon & U. Krengel (2002)
    High-Resolution crystal structures of Erythrina cristagalli lectin in complex with lactose and 2´-α-L-fucosyllactose and correlation with thermodynamic binding data,
    J. Mol. Biol. 321, 69-83. [PubMed]

  20. U. Krengel,  L.-L. Olsson, C. Martínez, A. Talavera, G. Rojas, E. Mier, J. Ångström & E. Moreno (2004)
    Structure and molecular interactions of a unique anti-tumor antibody specific for N-glycolyl GM3
    J. Biol. Chem. 279(7), 5597-5603. [PubMed]

  21. C. Oswald, T. Johansson, S. Törnroth & U. Krengel (2004)
    Crystallization and preliminary crystallographic analysis of the NAD(H) binding domain of Escherichia coli transhydrogenase
    Acta Crystallogr. D60, 743-745. [PubMed]

  22. Å. Holmner, M. Lebens, S. Teneberg, J. Ångström, M. Ökvist & U. Krengel (2004)
    Novel binding site identified in a hybrid between cholera toxin and heat-labile enterotoxin: 1.9 Å crystal structure reveals the details
    Structure 12 (9), 1655-1667. [PubMed]

  23. G. Rojas, A. Talavera, Y. Munoz, E. Rengifo, U. Krengel, J. Ångström, J. Gavilondo & E. Moreno (2004)
    Light chain shuffling results in successful phage display of antibody fragments to N-glycolyl GM3 ganglioside
    J. Immun. Meth. 293 (1-2), 71-83. [PubMed]

  24. E. Grahn, Å. Holmner, C. Cronet, H. Tateno, H. C. Winter, I. J. Goldstein & U. Krengel (2004)
    Crystallization and preliminary X-ray crystallographic studies of a lectin from the mushroom Marasmius oreades
    Acta Crystallogr. D60, 2038-2039. [PubMed]

  25. T. Johansson, C. Oswald, A. Pedersen, S. Törnroth, M. Ökvist, G. B. Karlsson, J. Rydström & U. Krengel (2005)
    X-ray structure of domain I of the proton-pumping membrane protein transhydrogenase from Escherichia coli
    J. Mol. Biol. 352(2), 299-312. [PubMed]

  26. M. Ökvist, R. Dey, S. Sasso, E. Grahn, P. Kast & U. Krengel (2006)
    1.6 Å crystal structure of the secreted chorismate mutase from Mycobacterium tuberculosis: Novel fold topology revealed
    J. Mol. Biol. 357, 1483-1499. [PubMed]

  27. U. Krengel, R. Dey, S. Sasso, M. Ökvist, C. Ramakrishnan & P. Kast (2006)
    Preliminary crystallographic analysis of the secreted chorismate mutase from Mycobacterium tuberculosis: A tricky crystallization problem solved
    Acta Crystallogr. F62, 441-445. [PubMed]

  28. E. Grahn, G. Askarieh, Å. Holmner, H. Tateno, H. C. Winter, I. J. Goldstein & U. Krengel (2007)
    Crystal structure of the Marasmius oreades mushroom lectin in complex with a xenotransplantation epitope
    J. Mol. Biol. 369, 710-721. [PubMed]

  29. U. Krengel & A. Imberty (2007)
    Crystallography and lectin structure database
    In: Lectins: Analytical technologies (C. Nilsson, Ed.), Elsevier, pp. 15-50.

  30. Å. Holmner, G. Askarieh, M. Ökvist, U. Krengel (2007)
    Blood group antigen recognition by Escherichia coli heat-labile enterotoxin
    J. Mol. Biol. 371, 754-764. [PubMed]

  31. E. Grahn, H.C. Winter, H. Tateno, I.J. Goldstein & U. Krengel (2009)
    Structural characterization of a lectin from the mushroom Marasmius oreades in complex with the blood group B trisaccharide and calcium
    J. Mol. Biol. 390, 457-466. [PubMed]

  32. A. Talavera, R. Friemann, S. Gómez-Puerta, C. Martinez-Fleites, G. Garrido, A. Rabasa, A. López-Requena, A. Pupo, R.F. Johansen, O. Sánchez, U. Krengel & E. Moreno (2009)
    Nimotuzumab, an anti-tumor antibody that targets the epidermal growth factor, blocks ligand binding while permitting the active receptor conformation
    Cancer Res. 69, 5851-5859. [PubMed]

  33. M. Ökvist, S. Sasso, K. Roderer, P. Kast & U. Krengel (2009)
    A non-covalent complex of chorismate mutase and DAHP synthase from Mycobacterium tuberculosis: protein purification, crystallization and X-ray diffraction analysis
    Acta Cryst. F65, 1048-1052. [PubMed]

  34. S. Sasso, M. Ökvist, K. Roderer, M. Gamper, G. Codoni, U. Krengel & P. Kast (2009)
    Structure and function of a complex between chorismate mutase and DAHP synthase: Efficiency boost for the junior partner
    EMBO J. 28, 2128-2142. [PubMed]

  35. A. Talavera, A. Eriksson, M. Ökvist, A. López-Requena, Y. Fernández-Marrero, R. Pérez, E. Moreno & U. Krengel (2009)
    Crystal structure of an anti-ganglioside antibody, and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody
    Mol. Immunol. 46, 3466–3475. [PubMed]

  36. Ĺ. Holmner, A. Mackenzie & U. Krengel (2010)
    Hypothesis: Molecular basis of cholera blood-group dependence and implications for a world characterized by climate change
    FEBS Lett. 584, 2548-2555. [PubMed]